Efprox DS Dry Syrup2018-11-13T16:54:44+00:00
efprox ds dry-soltech-product

Cefpodoxime        –          100 mg

Each Outer carton contain 30 ml bottle

Efprox DS Dry Syrup contains cefpodoxime. It is a third generation oral antibiotic. Cefpodoxime is a drug which is active against both gram positive and gram negative bacteria. It is mainly used for otitis media, pharyngitis, sinusitis and gonorrhea.

  • Acute otitis media
  • Acute maxillary sinusitis
  • Community acquired pneumonia
  • Uncomplicated skin and skin structure infections
  • Uncomplicated urinary tract infections

Cefpodoxime is active against a broad spectrum of gram positive and gram negative baceteria. It causes inhibition of cell wall synthesis and produces bactericidal activity. Its active metabolite binds to penicillin binding protein 3 which causes inhibition of production of peptidoglycan.

Absorption

After oral administration the drug is absorbed from gastrointestinal

tract. Cefpodoxime is a prodrug, after administration it gets de-esterified

 to its active metabolite cepodoxime.

Distribution

About 22 to 33% of the drug is bound to serum, and 21 to 29% of the

drug is bound to plasma.

Excretion

Nearly about 29-33% of the drug is excreted in unchanged form in

urine within in 12hrs.

  • Hypersensitivity reaction
  • If patients are penicillin sensitive, caution should be exercised because cross sensitivity among beta lactum antibiotics has been documented and can occur in patients with history of penicillin sensitivity
  • Allergic reaction
  • Patient history of kidney or liver disease and stomach problems
  • Patient with surgery like dental surgery
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