Nefmic kid Tablet2018-11-11T17:54:05+05:30
nefmic kid-soltech-product

Mefanamic acid    –    100 mg

Each box contain 10 Blister strips of 10 tablets

Nefmic kid Tablet contains Mefenamic acid.

Mefenamic acid

It is a NSAID which is used for the treatment of pain. It decreases the swelling in inflammation and also uterine contractions. It also inhibits PG synthesis.

  • Potent analgesic
  • Acute pain
  • Antispasmodic
  • Smooth muscle spasm
  • It also blocks the substances which causes inflammation

Mefenamic acid

It produces its pharmacological action by binding to prostaglandin synthetase receptors COX-1 and COX-2 and causes the inhibition of its action.  As these plays a major role in causing inflammation.

Mefenamic acid


It is rapidly absorbed after oral administration. The mean peak levels of mefenamic acid are ranging from 10-20mcg/ml3. Co-administration of mefenamic with antacid increases the absorption rate of magnesium hydroxide.


It is well distributed in the body with 90% of the drug is bound to plasma protein. The volume of distribution of the drug is 1.06 l/kg. It is metabolized by liver cytochrome P450 enzyme CYP2C9 to 3-hydroxymethyl mefenamic acid (Metabolite I).


About 52% of the drug is excreted in urine as glucuronides of mefenamic acid. About 20% of the drug is excreted through urine.

  • Complicated acute abdominal conditions
  • Prolong half life can cause difficulty in achieving steady state of drug in body.
  • Patients with pregnancy and lactation
  • Cannot be substituted for corticosteroid therapy
  • Sedation
  • Difficulty in operating machinery
  • Dizziness
  • Suicidal behaviour
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