Oxav 625 Tablet2018-11-13T20:37:17+05:30
oxav 625-soltech-product

Amoxycillin      –     500 mg

Potassium Clavulanate Diluted    –     125 mg

Each box contain 1 Alu-Alu strips of 6 Tablets

Amoxicillin and clavulanic acid are antibiotics drugs belongs to penicillin group. These are the combination of antibiotics which are used for many infections. Amoxicillin is an analog of ampicillin and it is derived from penicillin nucleus. Clavulanic acid is a beta lactum structurally related to penicillin and inactivate the beta lactamase by blocking the active sites of these enzymes.

  • Treatment of recurrent or persistence acute otitis media in pediatric patients
  • Reduces the development of drug resistant bacteria
  • Used for severe infections and infections caused by susceptible bacteria
  • They are used modifying antibacterial activity

Avox is a combination of amoxicillin and clavulanic acid. It is a beta lactum structurally related to penicillin, it have the ability to block the active site of enzymes and causes inactivation of the wide variety of beta-lactumases. Clavulanic acid protects the amoxicillin from degradation.

Absorption

It is orally administered and well distributed in the body. The absorption analysis was made in pediatric patients as the concentration maximum of amoxicillin is 15.7±7.7 and for clavulanic acid it is 1.77±0.9.

Distribution

Both the component of avox does not bind highly with protein. About 25% of the amoxicillin is bound to human serum. 18% of the clavulanic acid is bound to serum.

Excretion

 The drug is excreted in unchanged form in urine, about 50-70% of amoxicillin and 25-40% of clavulanic acid.

  • Patients with the history of allergic reactions to penicillin
  • Patients with the history of hepatic dysfunction caused due to drug
  • Possess low toxicity
  • Ampicillin develop an erythematous skin rash
  • Superinfections with mycotic or bacterial pathogens should be kept in mind during therapy
  • Long used increased the risk of drug resistance
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