Ferrous Ascorbate
Eq. to elemental iron – 100 mg
Folic Acid – 1.5 mg
Zinc sulphate Monohydrate – 22.5 mg
Each box contain 3 Alu-Alu strips of 10 tablets
Ascoref Tablet is a combination of Ferrous ascorbate, Folic acid and Zinc sulphate.
Iron is the inorganic form of compound which occurs as mineral magnetite. It is also known as hematite.
Folic acid is a vitamin B complex found in green leafy vegetable. It is often used in food industry. The term folate refers to the deprotonated ion and folic acid to the neutral molecule, which both co-exist in water.
- Anemia caused by chronic diseases
- Iron deficiency
- Coughs caused by ACE inhibitors
- Learning problems
- Iron deficiency during pregnancy
Iron
It is required for the production of hemoglobin. It deficiency can cause decreased production of hemoglobin a microcytic, hypochromic anemia.
Folic acid
It is as such inactive but gets converted to tetrahydrofolic acid and metyhyltetrahydrofolate by the enzyme terahydrofolate. These are transported in cells through endocytosis. These are needed to maintain normal normal erythropoiesis, generate and use formate.
Iron
Absorption
The absorption of the drug depends on the salt form, dosing regimen, size of iron store. 10 to 35% of the dose is absorbed. In iron deficient patients 95% of the iron dose is absorbed
Distribution
After oral administration iron is transferred to bone marrow for the production of red blood cells. 90% of the drug is bound to plasma protein. The peak concentration is achieved in 2hrs.
Excretion
The drug is excreted through feces, urine, in shedding of skin or through perspiration.
Folic acid
Absorption
The drug after oral administration is well absorbed in the body
Distribution
It is highly bound to plasma protein. the metabolism of the drug is through liver.
Elimination
The maximum amount of drug is excreted in urine.
- Hypersensitivity to any of the ingredient
- Patients with iron overload states
- Haemochromatosis
- In patients with renal failure there may be a risk of zinc accumulation
